CD8+CD103+PD1+TIM3+ T cells in glioblastoma microenvironment correlate with prognosis.

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作者： Giulia,Romagnoli ^[1] ; Quintino Giorgio,D'Alessandris ^[2] ; Imerio,Capone ^[1] ; Andrea,Tavilla ^[3] ; Irene,Canini ^[1] ; Caterina,Lapenta ^[1] ; Mariachiara,Buccarelli ^[1] ; Martina,Giordano ^[4] ; Valentina,Tirelli ^[5] ; Massimo,Sanchez ^[5] ; Alessandra,Fragale ^[1] ; Stefano,Giannetti ^[4] ; Rina,Di Bonaventura ^[6] ; Liverana,Lauretti ^[2] ; Mauro,Biffoni ^[1] ; Lucia,Ricci-Vitiani ^[1] ; Roberto,Pallini ^[2] ; Lucia,Gabriele ^[1]

作者单位： Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy. ^[1] Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.;Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. ^[2] National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanità, Rome, Italy. ^[3] Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy. ^[4] Core Facility, Istituto Superiore di Sanità, Rome, Italy. ^[5] Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. ^[6]

关键词 PD1 TIM3 age disease outcome glioblastoma predictors tissue-resident memory T cells (Trm)

主题词人类(Humans);胶质母细胞瘤(Glioblastoma);预后(Prognosis);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);肿瘤微环境(Tumor Microenvironment)

DOI 10.1111/imm.13710

PMID 37884280

发布时间 2025-02-06

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