Novel insights into the ecDNA formation mechanism involving MSH3 in methotrexate‑resistant human colorectal cancer cells.

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第一作者： Xu,Wang

第一单位： Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.

作者： Xu,Wang ^[1] ; Yanan,Qu ^[1] ; Ruonan,Xing ^[1] ; Jing,Zhou ^[1] ; Yanghe,Liu ^[1] ; Huishu,Zhang ^[1] ; Jing,Zhu ^[1] ; Jinfa,Ma ^[1] ; Xiaobo,Cui ^[1] ; Tiantian,Song ^[1] ; Shukai,Xing ^[1] ; Guohua,Ji ^[1] ; Peng,Liu ^[1] ; Wenjing,Sun ^[1] ; Songbin,Fu ^[1] ; Xiangning,Meng ^[1]

作者单位： Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China. ^[1]

关键词 DNA double?strand breaks MutS homolog 3 cancer extrachromosomal DNAs methotrexate?resistance

主题词人类(Humans);甲氨蝶呤(Methotrexate);DNA结合蛋白质类(DNA-Binding Proteins);DNA修复(DNA Repair);染色体畸变(Chromosome Aberrations);结直肠肿瘤(Colorectal Neoplasms);DNA(DNA)

DOI 10.3892/ijo.2023.5582

PMID 37888748

发布时间 2023-11-14

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