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Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil.

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第一作者： Peng-Peng,Wu

第一单位： Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.;University of Chinese Academy of Sciences, Beijing, 100049, China.

作者： Peng-Peng,Wu ^[1] ; Bi-Rong,Cao ^[1] ; Fu-Yun,Tian ^[2] ; Zhao-Bing,Gao ^[3]

作者单位： Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.;University of Chinese Academy of Sciences, Beijing, 100049, China. ^[1] Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. tianfuyun@zidd.ac.cn.;Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. tianfuyun@zidd.ac.cn. ^[2] Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. zbgao@simm.ac.cn.;University of Chinese Academy of Sciences, Beijing, 100049, China. zbgao@simm.ac.cn.;Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. zbgao@simm.ac.cn. ^[3]

关键词 Antiseizure medications Brivaracetam Epilepsy Levetiracetam Padsevonil Synaptic vesicle protein 2A