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Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-<i>a</i>]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A.

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第一作者： Xuan,Yang

第一单位： Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.;Rapidly Emerging Antiviral Drug Development Initiative (READDI), Chapel Hill, North Carolina 27599, United States.

作者： Xuan,Yang ^[1] ; Han Wee,Ong ^[1] ; Rebekah J,Dickmander ^[2] ; Jeffery L,Smith ^[3] ; Jason W,Brown ^[4] ; William,Tao ^[4] ; Edcon,Chang ^[4] ; Nathaniel J,Moorman ^[5] ; Alison D,Axtman ^[1] ; Timothy M,Willson ^[1]

作者单位： Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.;Rapidly Emerging Antiviral Drug Development Initiative (READDI), Chapel Hill, North Carolina 27599, United States. ^[1] Rapidly Emerging Antiviral Drug Development Initiative (READDI), Chapel Hill, North Carolina 27599, United States.;Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.;Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.;Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States. ^[2] Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States. ^[3] Takeda Development Center Americas, Inc., San Diego, California 92121, United States. ^[4] Rapidly Emerging Antiviral Drug Development Initiative (READDI), Chapel Hill, North Carolina 27599, United States.;Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.;Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States. ^[5]

DOI 10.1021/acsomega.3c05377

PMID 37901516

发布时间 2024-02-10

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ACS omega

2023年8卷42期

39546-39561页

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2023年8卷42期

39546-39561页

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Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-<i>a</i>]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A.

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Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-<i>a</i>]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A.

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