Accelerating the in vitro emulation of Alzheimer's disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model.

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作者： Eunkyung Clare,Ko ^[1] ; Sarah,Spitz ^[1] ; Francesca Michela,Pramotton ^[1] ; Olivia M,Barr ^[2] ; Ciana,Xu ^[2] ; Georgios,Pavlou ^[1] ; Shun,Zhang ^[1] ; Alice,Tsai ^[2] ; Anna,Maaser-Hecker ^[2] ; Mehdi,Jorfi ^[2] ; Se Hoon,Choi ^[2] ; Rudolph E,Tanzi ^[2] ; Roger D,Kamm ^[1]

作者单位： Department of Mechanical Engineering and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States. ^[1] Genetics and Aging Research Unit, McCance Center for Brain Health, Mass General Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, United States. ^[2]

关键词 Alzheimer’s disease (AD)blood-brain barrier (BBB)microfluidics microphysiological system (MPS)neurospheres

DOI 10.3389/fbioe.2023.1251195

PMID 37901842

发布时间 2024-09-27

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Frontiers in bioengineering and biotechnology

2023年11卷

1251195页

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Accelerating the in vitro emulation of Alzheimer's disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model.

Frontiers in bioengineering and biotechnology

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Frontiers in bioengineering and biotechnology

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Accelerating the in vitro emulation of Alzheimer's disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model.

Frontiers in bioengineering and biotechnology

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Frontiers in bioengineering and biotechnology

相关期刊

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