Natural Selection Signatures in the Hondo and Ryukyu Japanese Subpopulations.

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第一作者： Xiaoxi,Liu

第一单位： Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.;Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.

作者： Xiaoxi,Liu ^[1] ; Masatoshi,Matsunami ^[2] ; Momoko,Horikoshi ^[3] ; Shuji,Ito ^[4] ; Yuki,Ishikawa ^[4] ; Kunihiko,Suzuki ^[5] ; Yukihide,Momozawa ^[5] ; Shumpei,Niida ^[6] ; Ryosuke,Kimura ^[7] ; Kouichi,Ozaki ^[8] ; Shiro,Maeda ^[9] ; Minako,Imamura ^[9] ; Chikashi,Terao ^[10]

作者单位： Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.;Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan. ^[1] Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara-Cho, Japan. ^[2] Laboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. ^[3] Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. ^[4] Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. ^[5] Core Facility Administration, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan. ^[6] Department of Human Biology and Anatomy, Graduate School of Medicine, University of the Ryukyus, Nishihara-Cho, Japan. ^[7] Medical Genome Center, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan. ^[8] Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara-Cho, Japan.;Division of Clinical Laboratory and Blood Transfusion, University of the Ryukyus Hospital, Okinawa, Japan. ^[9] Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.;Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.;The Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan. ^[10]

关键词 ALDH2 FastSMC Hondo Japanese Ryukyu iHS natural selection

主题词人类(Humans);等位基因(Alleles);基因频率(Gene Frequency);单倍型(Haplotypes);多态性, 单核苷酸(Polymorphism, Single Nucleotide);遗传选择(Selection, Genetic);日本(Japan)

DOI 10.1093/molbev/msad231

PMID 37903429

发布时间 2024-09-28

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