Detection of TDP-43 seeding activity in the olfactory mucosa from patients with frontotemporal dementia.

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第一作者： Elena,Fontana

第一单位： Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

作者： Elena,Fontana ^[1] ; Matilde,Bongianni ^[1] ; Alberto,Benussi ^[2] ; Erika,Bronzato ^[3] ; Carlo,Scialo ^[1] ; Luca,Sacchetto ^[4] ; Annachiara,Cagnin ^[5] ; Santina,Castriciano ^[6] ; Emanuele,Buratti ^[7] ; Fabrizio,Gardoni ^[8] ; Maria,Italia ^[9] ; Alberto,Schreiber ^[10] ; Chiara,Ferracin ^[10] ; Michele,Fiorini ^[11] ; Kathy L,Newell ^[12] ; Laura,Cracco ^[1] ; Holly J,Garringer ^[13] ; Maria Paola,Cecchini ^[13] ; Magdalini,Polymenidou ^[13] ; Alessandro,Padovani ^[1] ; Salvatore,Monaco ^[4] ; Giuseppe,Legname ^[2] ; Bernardino,Ghetti ^[3] ; Barbara,Borroni ^[1] ; Gianluigi,Zanusso ^[12]

作者单位： Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. ^[1] Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. ^[2] Department of Continuity of Care and Frailty, ASST Spedali Civili Brescia Hospital, Brescia, Italy. ^[3] Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland. ^[4] Department of Surgery, Dentistry, Paediatrics and Gynaecology, Otolaryngology Section, University of Verona, Verona, Italy. ^[5] Neurology Unit, Department of Neuroscience, University of Padova, Padua, Italy. ^[6] Padova Neuroscience Center (PNC), University of Padova, Padua, Italy. ^[7] Copan, S.P.A, Brescia, Italy. ^[8] International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy. ^[9] Department of Pharmacological and Biomolecular Sciences (DiSFeB) "Rodolfo Paoletti,", University of Milan, Milan, Italy. ^[10] Otorhinolaryngology Unit, Head and Neck Surgery, ASST Spedali Civili, University of Brescia, Brescia, Italy. ^[11] Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy. ^[12] Department of Pathology and Laboratory Medicine, School of Medicine, Indiana University, Indianapolis, Indiana, USA. ^[13]

关键词 TAR DNA-binding protein 43 frontotemporal dementia frontotemporal lobar degeneration olfactory mucosa seeding seeding amplification assays

主题词人类(Humans);额颞叶痴呆(Frontotemporal Dementia);额颞叶变性(Frontotemporal Lobar Degeneration);tau蛋白质类(tau Proteins);额叶(Frontal Lobe);神经元(Neurons);DNA结合蛋白质类(DNA-Binding Proteins)

DOI 10.1002/alz.13541

PMID 37908186

发布时间 2024-07-15

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