Evaluating immunological and inflammatory changes of treatment-experienced people living with HIV switching from first-line triple cART regimens to DTG/3TC <i>vs.</i> B/F/TAF: the DEBATE trial.

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第一作者： Andrea,Cossarizza

第一单位： Chair of Pathology and Immunology, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.

作者： Andrea,Cossarizza ^[1] ; Alessandro,Cozzi-Lepri ^[2] ; Marco,Mattioli ^[1] ; Annamaria,Paolini ^[1] ; Anita,Neroni ^[1] ; Sara,De Biasi ^[1] ; Domenico Lo,Tartaro ^[1] ; Rebecca,Borella ^[1] ; Lucia,Fidanza ^[1] ; Lara,Gibellini ^[1] ; Barbara,Beghetto ^[3] ; Enrica,Roncaglia ^[3] ; Giulia,Nardini ^[3] ; Jovana,Milic ^[3] ; Marianna,Menozzi ^[4] ; Gianluca,Cuomo ^[4] ; Margherita,Digaetano ^[4] ; Gabriella,Orlando ^[4] ; Vanni,Borghi ^[4] ; Giovanni,Guaraldi ^[5] ; Cristina,Mussini ^[5]

作者单位： Chair of Pathology and Immunology, University of Modena and Reggio Emilia School of Medicine, Modena, Italy. ^[1] Centre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME), Institute for Global Health, University College London (UCL), London, United Kingdom. ^[2] Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy. ^[3] Clinic of Infectious Diseases, Azienda Ospedaliero-Universitaria Policlinico of Modena, Modena, Italy. ^[4] Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.;Clinic of Infectious Diseases, Azienda Ospedaliero-Universitaria Policlinico of Modena, Modena, Italy. ^[5]

关键词 B/F/TAF CD4/CD8 ratio DTG/3TC HIV dual regimen three-drug regimen

主题词人类(Humans);HIV感染(HIV Infections);白细胞介素6(Interleukin-6);拉米夫定(Lamivudine);CD4-CD8比值(CD4-CD8 Ratio)

DOI 10.3389/fimmu.2023.1279390

PMID 37908359

发布时间 2023-11-05

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