Differential lipid analysis of oxaliplatin-sensitive and resistant HCT116 cells reveals different levels of drug-induced lipid droplet formation.

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作者： Tyler S,Larson ^[1] ; Thomas J,DiProspero ^[1] ; Gary L,Glish ^[2] ; Matthew R,Lockett ^[3]

作者单位： Department of Chemistry, University of North Carolina at Chapel Hill, Kenan and Caudill Laboratories, Chapel Hill, NC, 27599-3290, USA. ^[1] Department of Chemistry, University of North Carolina at Chapel Hill, Kenan and Caudill Laboratories, Chapel Hill, NC, 27599-3290, USA. glish@unc.edu. ^[2] Department of Chemistry, University of North Carolina at Chapel Hill, Kenan and Caudill Laboratories, Chapel Hill, NC, 27599-3290, USA. mlockett@unc.edu.;Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7295, USA. mlockett@unc.edu. ^[3]

关键词 Colorectal cancer Differential ion mobility spectrometry Mass spectrometry Shotgun lipidomics

主题词人类(Humans);HCT116细胞(HCT116 Cells);蛋白质组学(Proteomics);甘油三酯类(Triglycerides)

DOI 10.1007/s00216-023-05010-0

PMID 37917349

发布时间 2025-01-04

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