A Nanoemulgel for Nose-to-Brain delivery of Quetiapine - QbD-Enabled formulation development & in-vitro characterization.

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第一作者： Dnyandev,Gadhave

第一单位： Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, USA.

作者： Dnyandev,Gadhave ^[1] ; Mural,Quadros ^[1] ; Akanksha R,Ugale ^[1] ; Mimansa,Goyal ^[1] ; Vivek,Gupta ^[2]

作者单位： Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, USA. ^[1] Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, USA. Electronic address: guptav@stjohns.edu. ^[2]

关键词 Cellular permeation Chitosan Nanoemulgel Mental disorders Nose-to-brain delivery Quetiapine RPMI-2650 cells Transepithelial electrical resistance

主题词人类(Humans);泊洛沙姆(Poloxamer);壳聚糖(Chitosan);抗精神病药(Antipsychotic Agents);脑(Brain)

DOI 10.1016/j.ijpharm.2023.123566

PMID 37918496

发布时间 2023-12-17

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