Th17-inducing dendritic cell vaccines stimulate effective CD4 T cell-dependent antitumor immunity in ovarian cancer that overcomes resistance to immune checkpoint blockade.

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作者： Yan,Luo ^[1] ; Barath,Shreeder ^[1] ; James W,Jenkins ^[1] ; Huashan,Shi ^[1] ; Purushottam,Lamichhane ^[1] ; Kexun,Zhou ^[1] ; Deborah A,Bahr ^[1] ; Sophia,Kurian ^[1] ; Katherine A,Jones ^[1] ; Joshua I,Daum ^[1] ; Navnita,Dutta ^[1] ; Brian M,Necela ^[1] ; Martin J,Cannon ^[2] ; Matthew S,Block ^[3] ; Keith L,Knutson ^[4]

作者单位： Department of Immunology, Mayo Clinic in Florida, Jacksonville, Florida, USA. ^[1] Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. ^[2] Divison of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA. ^[3] Department of Immunology, Mayo Clinic in Florida, Jacksonville, Florida, USA knutson.keith@mayo.edu. ^[4]

关键词 Antigens CD4-Positive T-Lymphocytes Immunomodulation Immunotherapy, Active Tumor Escape

主题词人类(Humans);女(雌)性(Female);小鼠(Mice);动物(Animals);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);卵巢肿瘤(Ovarian Neoplasms);树突细胞(Dendritic Cells);肿瘤微环境(Tumor Microenvironment)

DOI 10.1136/jitc-2023-007661

PMID 37918918

发布时间 2024-02-10

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Journal for immunotherapy of cancer

2023年11卷11期

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Th17-inducing dendritic cell vaccines stimulate effective CD4 T cell-dependent antitumor immunity in ovarian cancer that overcomes resistance to immune checkpoint blockade.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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Th17-inducing dendritic cell vaccines stimulate effective CD4 T cell-dependent antitumor immunity in ovarian cancer that overcomes resistance to immune checkpoint blockade.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

相关期刊

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