A sensitive AAV transduction inhibition assay assists evaluation of critical factors for detection and concordance of pre-existing antibodies.

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第一作者： Yonghua,Pan

第一单位： Sangamo Therapeutics, Inc, 7000 Marina Boulevard, Brisbane, CA 94005, USA.

作者： Yonghua,Pan ^[1] ; Michelle,Rohde ^[1] ; Jennifer,Zeitler ^[1] ; Sai Valli Srujana,Namburi ^[1] ; Liching,Cao ^[1] ; Jing,Hu ^[1] ; Kathleen,Meyer ^[1] ; Yanmei,Lu ^[1]

作者单位： Sangamo Therapeutics, Inc, 7000 Marina Boulevard, Brisbane, CA 94005, USA. ^[1]

关键词 adeno-associated virus clinical enrollment assay comparative analysis neutralizing antibodies pre-existing humoral immunity seropositivity concordance total antibodies total antibody assay transduction inhibition assay

DOI 10.1016/j.omtm.2023.101126

PMID 37920239

发布时间 2024-09-30

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Molecular therapy. Methods & clinical development

2023年31卷

101126页

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A sensitive AAV transduction inhibition assay assists evaluation of critical factors for detection and concordance of pre-existing antibodies.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

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A sensitive AAV transduction inhibition assay assists evaluation of critical factors for detection and concordance of pre-existing antibodies.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

相关期刊

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