The inhibition of inner mitochondrial fusion in hepatocytes reduces non-alcoholic fatty liver and improves metabolic profile during obesity by modulating bile acid conjugation.

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第一作者： Lorenzo,Da Dalt

第一单位： Department of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", Università Degli Studi di Milano, Via Balzaretti 9, 20133 Milan, Italy.

作者： Lorenzo,Da Dalt ^[1] ; Annalisa,Moregola ^[1] ; Monika,Svecla ^[1] ; Silvia,Pedretti ^[1] ; Francesca,Fantini ^[1] ; Mirko,Ronzio ^[2] ; Patrizia,Uboldi ^[1] ; Diletta,Dolfini ^[2] ; Elena,Donetti ^[3] ; Andrea,Baragetti ^[1] ; Nico,Mitro ^[1] ; Luca,Scorrano ^[4] ; Giuseppe Danilo,Norata ^[5]

作者单位： Department of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", Università Degli Studi di Milano, Via Balzaretti 9, 20133 Milan, Italy. ^[1] Dipartiment of Biosciences, Università Degli Studi di Milano,Via Celoria 26, 20133 Milan, Italy. ^[2] Department of Biomedical Science for Health, Università Degli Studi di Milano, Via Mangiagalli, 31, 20133 Milan, Italy. ^[3] Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy. ^[4] Department of Biology, University of Padova, Via U. Bassi 58B, 35121 Padova, Italy. ^[5] Veneto Institute of Molecular Medicine, Via Orus 2, 35129 Padova, Italy. ^[6] Center for the Study of Atherosclerosis, E. Bassini Hospital, Via Massimo Gorki 50, Cinisello Balsamo, Italy. ^[7]

关键词 Bile acids Dietary lipid absorption Liver Mitochondria