An expanded toolkit of drug resistance cassettes for Candida glabrata, Candida auris, and Candida albicans leads to new insights into the ergosterol pathway.

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第一作者： Justin B,Gregor

第一单位： Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.

作者： Justin B,Gregor ^[1] ; Victor A,Gutierrez-Schultz ^[1] ; Smriti,Hoda ^[1] ; Kortany M,Baker ^[1] ; Debasmita,Saha ^[1] ; Madeline G,Burghaze ^[1] ; Cynthia,Vazquez ^[1] ; Kendra E,Burgei ^[1] ; Scott D,Briggs ^[2]

作者单位： Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA. ^[1] Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.;Purdue University Institute for Cancer Research, West Lafayette, Indiana, USA. ^[2]

关键词 CRISPR-RNP Candida albicans Candida auris Candida glabrata ERG5 and ERG3 KanMX and BleMX antifungal drug resistance azole antifungal drugs ergosterol pathway toxic sterols

主题词白色念珠菌(Candida albicans);光滑念珠菌(Candida glabrata);抗真菌药(Antifungal Agents);麦角固醇(Ergosterol);念珠菌属(Candida);抗药性, 真菌(Drug Resistance, Fungal)

DOI 10.1128/msphere.00311-23

PMID 37929964

发布时间 2023-12-22

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2023年8卷6期

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An expanded toolkit of drug resistance cassettes for <i>Candida glabrata</i>, <i>Candida auris</i>, and <i>Candida albicans</i> leads to new insights into the ergosterol pathway.

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An expanded toolkit of drug resistance cassettes for <i>Candida glabrata</i>, <i>Candida auris</i>, and <i>Candida albicans</i> leads to new insights into the ergosterol pathway.

mSphere

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