换一批
换一批PP2A inhibition causes synthetic lethality in BRCA2-mutated prostate cancer models via spindle assembly checkpoint reactivation.
第一作者：
Jian,Wang
第一单位：
Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Beijing Key Laboratory of Tumor Systems Biology, Peking University Health Science Center, Beijing, China.
作者：
主题词
动物(Animals);人类(Humans);男(雄)性(Male);BRCA2蛋白质(BRCA2 Protein);秀丽新小杆线虫(Caenorhabditis elegans);哺乳动物(Mammals);突变(Mutation);前列腺肿瘤(Prostatic Neoplasms);泛素硫酯酶(Ubiquitin Thiolesterase);蛋白质磷酸酶2(Protein Phosphatase 2)
DOI
10.1172/JCI172137
PMID
37934606
发布时间
2024-01-08
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