snRNA-seq analysis in multinucleated myogenic FSHD cells identifies heterogeneous FSHD transcriptome signatures associated with embryonic-like program activation and oxidative stress-induced apoptosis.
第一作者:
Dongxu,Zheng
第一单位:
Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
作者:
主题词
人类(Humans);肌营养不良, 面肩肱型(Muscular Dystrophy, Facioscapulohumeral);同源盒结构域蛋白质类(Homeodomain Proteins);RNA, 小核(RNA, Small Nuclear);氧化性应激(Oxidative Stress);细胞凋亡(Apoptosis);肌, 骨骼(Muscle, Skeletal);基因表达调控(Gene Expression Regulation)
DOI
10.1093/hmg/ddad186
PMID
37934801
发布时间
2024-11-13
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Human molecular genetics
284-298页
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