Talazoparib enhances the quinacrine-mediated apoptosis in patient-derived oral mucosa CSCs by inhibiting BER pathway through the modulation of GCN5 and P300.
第一作者:
Chinmay,Das
第一单位:
Cancer Biology Division, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Campus-11, Patia, Bhubaneswar, Odisha, 751024, India.
作者:
医学主题词
人类(Humans);动物(Animals);小鼠(Mice);奎纳克林(Quinacrine);口腔黏膜(Mouth Mucosa);DNA修复(DNA Repair);抗肿瘤药(Antineoplastic Agents);DNA损伤(DNA Damage);染色质(Chromatin);DNA(DNA);细胞凋亡(Apoptosis)
DOI
10.1007/s12032-023-02222-3
PMID
37940725
发布时间
2023-11-20
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