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Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup.

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第一作者: Senthilkumar,Ramamoorthy
第一单位: Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
作者单位: Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. [1] Institute of Medical Bioinformatics and Systems Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. [2] Human Genetics, University of Magdeburg, Magdeburg, Germany. [3] Faculty of Biology, University of Freiburg, Freiburg, Germany. [4] Department of Pediatric Hematology and Oncology, Dr. v. Hauner Children's Hospital, University Hospital, LMU, Munich, Germany. [5] Department of Pediatric Oncology, Hematology and Immunology, University of Dusseldorf, Dusseldorf, Germany. [6] Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands. [7] Department of Pediatric Hematology and Oncology, Oslo University Hospital, Oslo, Norway. [8] Department of Hematology and Oncology, Hospital Sant Joan de Déu, Barcelona, Spain. [9] Diagnostic Laboratory/DCOG Laboratory, Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands. [10] St. Anna Children's Cancer Research Institute, Vienna, Austria. [11] Department of Pediatrics and Adolescent Medicine, St. Anna Children's Hospital, Medical University of Vienna, Vienna, Austria. [12] German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), partner site Freiburg, Freiburg, Germany. [13] Department of Pediatrics, Aarhus University Hospital Skejby, Aarhus, Denmark. [14] Division of Hematology-Oncology and Stem Cell Transplantation, Children's Hospital, Helsinki University Hospital, Helsinki, Finland. [15] Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, Catholic University of the Sacred Heart, Rome, Italy. [16] Pediatric Oncology and Hematology Unit "Lalla Seràgnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. [17] Department of Pediatric Hematology/ Oncology, Charles University and Univ Hospital Motol, Prague, Czech Republic. [18] Department of Pediatric Oncology/Hematology, Skåne University Hospital, Lund, Sweden. [19]
DOI 10.1111/bjh.19190
PMID 37945316
发布时间 2024-03-05
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British journal of haematology

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