Size-tunable nanogels for cascaded release of metronidazole and chemotherapeutic agents to combat Fusobacterium nucleatum-infected colorectal cancer.

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第一作者： Shuang,Xie

第一单位： Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu 610031, PR China; Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.

作者： Shuang,Xie ^[1] ; Li,Wei ^[2] ; Yuan,Liu ^[3] ; Jie,Meng ^[1] ; Wenxiong,Cao ^[1] ; Bo,Qiu ^[3] ; Xiaohong,Li ^[4]

作者单位： Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu 610031, PR China; Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China. ^[1] Department of Pathology, Western Theater Command Air Force Hospital, Chengdu 610021, PR China. ^[2] Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China. ^[3] Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu 610031, PR China; Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China. Electronic address: xhli@swjtu.edu.cn. ^[4]

关键词 Cascaded drug release Dual responsiveness, size paradox Fusobacterium nucleatum-infected cancer Size-tunable nanogel