A new contingent screening strategy increased detection rate of trisomy 21 in the first trimester.

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作者： Wei,Luo ^[1] ; Bin,He ^[2] ; Daiwen,Han ^[3] ; Lixing,Yuan ^[1] ; Jun,Tang ^[2] ; Ling,Pang ^[3] ; Fene,Zou ^[1] ; Kai,Zhao ^[2] ; Shanling,Liu ^[3] ; Ting,Hu ^[1]

作者单位： Department of Medical Genetics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. ^[1] Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. ^[2] Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, 610041, China. ^[3] Department of Medical Genetics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. huting4123@163.com. ^[4] Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. huting4123@163.com. ^[5] Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, 610041, China. huting4123@163.com. ^[6]

关键词 Contingent screening strategy First-trimester screening Non-invasive prenatal screening Prenatal diagnosis Serum biochemical screening Trisomy 21