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FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters.

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作者单位: Division of Cancer Cell Biology, Cancer Research Institute, and. [1] Institute for Frontier Science Initiative, Kanazawa University, Kanazawa City, Japan. [2] Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan. [3] Department of Oncology-Pathology, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. [4] Division of Systems Biology, Graduate School of Medicine, Nagoya University, Nagoya City, Japan. [5] Department of Breast and Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. [6] Department of Surgery, Minami-machida Hospital, Machida City, Tokyo, Japan. [7] Department of Breast Oncology, Kanazawa University Hospital, Kanazawa City, Japan. [8] Department of Breast and Endocrine Surgery, Nihon University, Itabashi-ku, Tokyo, Japan. [9] Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. [10] Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. [11] North Shore Heart Research Group, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia. [12] Department of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama City, Kanagawa, Japan. [13] Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan. [14] Department of Systems Biomedicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan. [15] Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan. [16] Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama City, Kanagawa, Japan. [17] Laboratory of Computational Genomics, Institute for Quantitative Biosciences. [18] Department of Computational Biology and Medical Sciences, Graduate School of Frontier Biosciences. [19] Department of Cardiovascular Medicine, Graduate School of Medicine. [20] Genome Science Division, Research Center for Advanced Science and Technology. [21] Department of Frontier Cardiovascular Science, Graduate School of Medicine, and. [22] Institute of Medical Science, The University of Tokyo, Tokyo, Japan. [23] Inflammation and Epithelial Plasticity Unit, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan. [24] Advanced Comprehensive Research Organization, Teikyo University, Itabashi-ku, Tokyo, Japan. [25]
DOI 10.1172/JCI166666
PMID 37966117
发布时间 2024-02-14
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The Journal of clinical investigation

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