Bleeding phenotype and hemostatic evaluation by thrombin generation in children with Noonan syndrome: A prospective study.

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第一作者： Assaf A,Barg

第一单位： National Hemophilia Center, Coagulation Unit and Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Ashdod, Israel.

作者： Assaf A,Barg ^[1] ; Yonatan,Yeshayahu ^[2] ; Einat,Avishai ^[1] ; Ivan,Budnik ^[3] ; Omri,Cohen ^[1] ; Tami,Brutman-Barazani ^[1] ; Rima,Dardik ^[1] ; Annick,Raas-Rothschild ^[4] ; Sarina,Levy-Mendelovich ^[5] ; Tami,Livnat ^[1] ; Orit,Pinhas-Hamiel ^[6] ; Gili,Kenet ^[1]

作者单位： National Hemophilia Center, Coagulation Unit and Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Ashdod, Israel. ^[1] Pediatrics Department, Samson Assuta Ashdod Hospital, Ashdod, Israel.;Noonan Multidisciplinary Clinic, Pediatric Endocrinology and Diabetes Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.;Faculty of Health Sciences, Ben-Gurion University, Beer Sheva, Ashdod, Israel. ^[2] Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA. ^[3] The Institute for Rare Diseases, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Ashdod, Israel. ^[4] National Hemophilia Center, Coagulation Unit and Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Ashdod, Israel.;Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel. ^[5] Noonan Multidisciplinary Clinic, Pediatric Endocrinology and Diabetes Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.;Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel. ^[6]

关键词 Noonan syndrome bleeding light transmission aggregometry surgery thrombin generation