Improving DNA vaccination performance through a new microbubble design and an optimized sonoporation protocol.

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第一作者： Yuanchao,Shi

第一单位： School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, Guangdong, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen 518055, Guangdong, China.

作者： Yuanchao,Shi ^[1] ; Weixiong,Weng ^[1] ; Mengting,Chen ^[1] ; Haoqiang,Huang ^[1] ; Xin,Chen ^[1] ; Yin,Peng ^[2] ; Yaxin,Hu ^[3]

作者单位： School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, Guangdong, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen 518055, Guangdong, China. ^[1] School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, Guangdong, China. ^[2] School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, Guangdong, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen 518055, Guangdong, China. Electronic address: yxhu@szu.edu.cn. ^[3]

关键词 DNA-loading capacity Long-term expression Microbubble Sustained antibody level Ultrasound Whole genome resequencing

主题词微气泡(Microbubbles);质粒(Plasmids);疫苗, DNA(Vaccines, DNA);DNA(DNA);接种(Vaccination)

DOI 10.1016/j.ultsonch.2023.106685

PMID 37976565

发布时间 2023-12-22

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