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FOXO1 is a master regulator of CAR T memory programming.

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作者单位: Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. [1] Department of Pediatrics, Division of Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 USA. [2] Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. [3] Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. [4] Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [5] Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [6] Department of Pathology, Stanford University, Stanford, CA 94305, USA. [7] Department of Bioengineering, Stanford University, Stanford, CA 94305, USA. [8] Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA. [9] Cell and Molecular Biology Graduate Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. [10] Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA. [11] Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [12] Parker Institute for Cancer Immunotherapy, San Francisco, CA 94129 USA. [13] Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [14] Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA. [15] Division of Blood and Marrow Transplantation and Cell Therapy, Department of Medicine, Stanford University, Stanford, CA 94305, USA. [16]
DOI 10.21203/rs.3.rs-2802998/v1
PMID 37986944
发布时间 2024-04-23
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