Next-generation forward genetic screens: uniting high-throughput perturbations with single-cell analysis.

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作者： John A,Morris ^[1] ; Jennifer S,Sun ^[1] ; Neville E,Sanjana ^[2]

作者单位： New York Genome Center, New York, NY 10013, USA; Department of Biology, New York University, New York, NY 10003, USA. ^[1] New York Genome Center, New York, NY 10013, USA; Department of Biology, New York University, New York, NY 10003, USA. Electronic address: neville@sanjanalab.org. ^[2]

关键词 CRISPR functional genomics genome engineering guide RNA capture multimodal sequencing multiomics single-cell sequencing

主题词基因组(Genome);基因检测(Genetic Testing);单细胞分析(Single-Cell Analysis)

DOI 10.1016/j.tig.2023.10.012

PMID 37989654

发布时间 2025-02-02

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