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Benchmarking MicrobIEM - a user-friendly tool for decontamination of microbiome sequencing data.

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第一作者： Claudia,Hülpüsch

第一单位： Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.;Chair of Environmental Medicine, Technical University of Munich, Munich, Germany.;CK CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland.

作者： Claudia,Hülpüsch ^[1] ; Luise,Rauer ^[2] ; Thomas,Nussbaumer ^[3] ; Vera,Schwierzeck ^[4] ; Madhumita,Bhattacharyya ^[5] ; Veronika,Erhart ^[6] ; Claudia,Traidl-Hoffmann ^[7] ; Matthias,Reiger ^[2] ; Avidan U,Neumann ^[8]

作者单位： Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.;Chair of Environmental Medicine, Technical University of Munich, Munich, Germany.;CK CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland. ^[1] Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.;Chair of Environmental Medicine, Technical University of Munich, Munich, Germany.;Institute of Environmental Medicine, Helmholtz Munich, Augsburg, Germany. ^[2] Institute of Environmental Medicine, Helmholtz Munich, Augsburg, Germany. ^[3] Institute of Environmental Medicine, Helmholtz Munich, Augsburg, Germany.;Institute of Hygiene, University Hospital Muenster, Muenster, Germany. ^[4] Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.;Chair of Environmental Medicine, Technical University of Munich, Munich, Germany. ^[5] Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany. ^[6] Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.;Chair of Environmental Medicine, Technical University of Munich, Munich, Germany.;CK CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland.;Institute of Environmental Medicine, Helmholtz Munich, Augsburg, Germany.;ZIEL - Institute for Food & Health, Technical University of Munich, Freising-Weihenstephan, Germany. ^[7] Environmental Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany. avidan.neumann@uni-a.de.;Institute of Environmental Medicine, Helmholtz Munich, Augsburg, Germany. avidan.neumann@uni-a.de. ^[8]

关键词 16S rRNA gene sequencing Bioinformatic decontamination Decontam Low-biomass microbiome Negative control SourceTracker Youden’s index

医学主题词人类(Humans);细菌(Bacteria);规范(Benchmarking);RNA, 核糖体, 16S(RNA, Ribosomal, 16S);净化(Decontamination);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);序列分析, DNA(Sequence Analysis, DNA)

DOI 10.1186/s12915-023-01737-5

PMID 37996810

发布时间 2024-01-08

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准确一般字义偏差语意偏离译文作用小提交