Identifying Genes Associated with Alzheimer's Disease Using Gene-Based Polygenic Risk Score.

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作者： Dongbing,Lai ^[1] ; Michael,Zhang ^[1] ; Rudong,Li ^[1] ; Chi,Zhang ^[1] ; Pengyue,Zhang ^[2] ; Yunlong,Liu ^[1] ; Sujuan,Gao ^[2] ; Tatiana,Foroud ^[1]

作者单位： Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. ^[1] Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA. ^[2]

关键词 Alzheimer’s disease SNP heritability gene co-expression module gene-based polygenic risk score gene-targeting drugs protein-protein interaction network

主题词人类(Humans);阿尔茨海默病(Alzheimer Disease);全基因组关联研究(Genome-Wide Association Study);基因调控网络(Gene Regulatory Networks)

DOI 10.3233/JAD-230510

PMID 38007651

发布时间 2024-06-07

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