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A second-generation M1-polarized CAR macrophage with antitumor efficacy.

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作者: Anhua,Lei [1] ; Hua,Yu [2] ; Shan,Lu [3] ; Hengxing,Lu [4] ; Xizhong,Ding [1] ; Tianyu,Tan [5] ; Hailing,Zhang [6] ; Mengmeng,Zhu [2] ; Lin,Tian [1] ; Xudong,Wang [2] ; Siyu,Su [1] ; Dixuan,Xue [2] ; Shaolong,Zhang [1] ; Wei,Zhao [2] ; Yuge,Chen [1] ; Wanrun,Xie [1] ; Li,Zhang [3] ; Yuqing,Zhu [1] ; Jing,Zhao [2] ; Wenhong,Jiang [7] ; George,Church [2] ; Francis Ka-Ming,Chan [2] ; Zhihua,Gao [8] ; Jin,Zhang [9]
作者单位: Center for Stem Cell and Regenerative Medicine, Department of Basic Medical Sciences, and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. [1] Liangzhu Laboratory, Zhejiang University, Hangzhou, China. [2] Institute of Hematology, Zhejiang University, Hangzhou, China. [3] CellOrigin Inc, Hangzhou, China. [4] School of Basic Medical Sciences, Nanchang University, Nanchang, China. [5] Department of Surgical Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China. [6] Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China. [7] Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, China. [8] MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, Hangzhou, China. [9] NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou, China. [10] Department of Genetics and Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA, USA. [11] Center for Stem Cell and Regenerative Medicine, Department of Basic Medical Sciences, and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. zhgene@zju.edu.cn. [12] Liangzhu Laboratory, Zhejiang University, Hangzhou, China. zhgene@zju.edu.cn. [13] Institute of Hematology, Zhejiang University, Hangzhou, China. zhgene@zju.edu.cn. [14] Center of Gene and Cell Therapy and Genome Medicine of Zhejiang Province, Hangzhou, China. zhgene@zju.edu.cn. [15]
DOI 10.1038/s41590-023-01687-8
PMID 38012418
发布时间 2024-03-01
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