Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases.

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作者： Yuqin,Liang ^[1] ; Xihao,Sun ^[2] ; Chunwen,Duan ^[1] ; Shibo,Tang ^[2] ; Jiansu,Chen ^[1]

作者单位： Aier Eye Institute, Changsha, 410015, China. ^[1] Eye Center of Xiangya Hospital, Central South University, Changsha, 410008, China. ^[2] Changsha Aier Eye Hospital, Changsha, 410015, China. ^[3] Aier Eye Institute, Changsha, 410015, China. tangshibo@vip.163.com. ^[4] Changsha Aier Eye Hospital, Changsha, 410015, China. tangshibo@vip.163.com. ^[5] Aier Eye Institute, Changsha, 410015, China. chenjiansu2000@163.com. ^[6] Changsha Aier Eye Hospital, Changsha, 410015, China. chenjiansu2000@163.com. ^[7] Key Laboratory for Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou, 510632, China. chenjiansu2000@163.com. ^[8]

关键词 Disease modeling Induced pluripotent stem cell Inherited retinal disease Retinal organoid Tissue engineering

主题词动物(Animals);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);视网膜(Retina);视网膜变性(Retinal Degeneration);色素性视网膜炎(Retinitis Pigmentosa);类器官(Organoids)

DOI 10.1186/s13287-023-03564-5

PMID 38012786

发布时间 2024-01-25

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