首页> Journal for immunotherapy of cancer> High-dimensional single-cell proteomics analysis of esophageal squamous cell carcinoma reveals dynamic alterations of the tumor immune microenvironment after neoadjuvant therapy.

High-dimensional single-cell proteomics analysis of esophageal squamous cell carcinoma reveals dynamic alterations of the tumor immune microenvironment after neoadjuvant therapy.

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第一作者： Dingpei,Han

第一单位： Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

作者： Dingpei,Han ^[1] ; Yichao,Han ^[1] ; Wei,Guo ^[1] ; Wei,Wei ^[2] ; Su,Yang ^[1] ; Jie,Xiang ^[1] ; Jiaming,Che ^[1] ; Lianggang,Zhu ^[1] ; Junbiao,Hang ^[1] ; Tom,van den Ende ^[3] ; Hanneke W M,van Laarhoven ^[3] ; Bin,Li ^[4] ; Youqiong,Ye ^[5] ; Hecheng,Li ^[6]

作者单位： Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ^[1] Department of Esophageal Surgery, Department of Thoracic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. ^[2] Department of Medical Oncology, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands. ^[3] Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Department of Thoracic Surgery of Ruijin Hospital, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.;Department of Thoracic Surgery, Clinical Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.;Department of Integrated TCM & Western Medicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China. ^[4] Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China lihecheng2000@hotmail.com youqiong.ye@shsmu.edu.cn. ^[5] Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China lihecheng2000@hotmail.com youqiong.ye@shsmu.edu.cn. ^[6]

关键词 Immune Checkpoint Inhibitors Radiotherapy Tumor Biomarkers Tumor Microenvironment

医学主题词人类(Humans);肿瘤辅助疗法(Neoadjuvant Therapy);食管肿瘤(Esophageal Neoplasms);癌, 鳞状细胞(Carcinoma, Squamous Cell);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);蛋白质组学(Proteomics);肿瘤微环境(Tumor Microenvironment)

DOI 10.1136/jitc-2023-007847

PMID 38016720

发布时间 2024-01-05

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