Fluorescence-Based Peptidolytic Assay for High-Throughput Screening of MMP14 Inhibitors.

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第一作者： Hyun,Lee

第一单位： Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.;Biophysics Core at the Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA.

作者： Hyun,Lee ^[1] ; Lucas,Ibrahimi ^[2] ; Kyu-Yeon,Han ^[3]

作者单位： Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.;Biophysics Core at the Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA. ^[1] Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA. ^[2] Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA. biohan72@uic.edu. ^[3]

关键词 Enzyme kinetic assay Fluorescence-based enzyme assays High-throughput screening MMP14 Matrix metalloproteinase

主题词人类(Humans);基质金属蛋白酶14(Matrix Metalloproteinase 14);高通量筛选分析(High-Throughput Screening Assays);肽类(Peptides);肿瘤(Neoplasms);伤口愈合(Wound Healing)

DOI 10.1007/978-1-0716-3589-6_18

PMID 38038944

发布时间 2024-08-21

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