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Age-dependent genetic regulation of osteoarthritis: independent effects of immune system genes.

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第一作者： Jacob,Kenny

第一单位： School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Jacob.kenny@uwa.edu.au.

作者： Jacob,Kenny ^[1] ; Benjamin H,Mullin ^[2] ; William,Tomlinson ^[3] ; Brett,Robertson ^[4] ; Jinbo,Yuan ^[3] ; Weiwei,Chen ^[5] ; Jinmin,Zhao ^[5] ; Nathan J,Pavlos ^[3] ; John P,Walsh ^[6] ; Scott G,Wilson ^[7] ; Jennifer,Tickner ^[3] ; Grant,Morahan ^[8] ; Jiake,Xu ^[9]

作者单位： School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Jacob.kenny@uwa.edu.au. ^[1] School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.;Department of Endocrinology & Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia. ^[2] School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia. ^[3] Australian Institute of Robotic Orthopaedics, Crawley, WA, Australia. ^[4] Research Centre for Regenerative Medicine, and Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Guangxi, China. ^[5] Department of Endocrinology & Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.;Medical School, University of Western Australia, Crawley, WA, Australia. ^[6] School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.;Department of Endocrinology & Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.;Department of Twin Research & Genetic Epidemiology, King's College London, London, UK. ^[7] Centre for Diabetes Research, Harry Perkins Institute for Medical Research, Nedlands, WA, Australia. grant.morahan@perkins.org.au. ^[8] School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.;Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. ^[9]

关键词 Genetics Genome-wide association Immune regulation Osteoarthritis