Comprehensive analysis of the proximity-dependent nuclear interactome for the oncoprotein NOTCH1 in live cells.

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作者： Haydee M,Torres ^[1] ; Fang,Fang ^[2] ; Danielle G,May ^[3] ; Paige,Bosshardt ^[2] ; Leetoria,Hinojosa ^[2] ; Kyle J,Roux ^[4] ; Jianning,Tao ^[5]

作者单位： Cancer Biology & Immunotherapies Group, Sanford Research, Sioux Falls, South Dakota, USA; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, South Dakota, USA. ^[1] Cancer Biology & Immunotherapies Group, Sanford Research, Sioux Falls, South Dakota, USA. ^[2] Enabling Technologies Group, Sanford Research, Sioux Falls, South Dakota, USA. ^[3] Enabling Technologies Group, Sanford Research, Sioux Falls, South Dakota, USA; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota, USA. ^[4] Cancer Biology & Immunotherapies Group, Sanford Research, Sioux Falls, South Dakota, USA; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, South Dakota, USA; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota, USA. Electronic address: Jianning.Tao@Sanfordhealth.org. ^[5]

关键词 BioID HDAC1 NICD NOTCH1 Notch pathway Proteomics cancer network analysis protein-protein interaction