A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease.

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第一作者： Vinita,Bharat

第一单位： Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

作者： Vinita,Bharat ^[1] ; Aarooran S,Durairaj ^[1] ; Roeland,Vanhauwaert ^[1] ; Li,Li ^[1] ; Colin M,Muir ^[2] ; Sujyoti,Chandra ^[1] ; Chulhwan S,Kwak ^[1] ; Yann,Le Guen ^[3] ; Pawan,Nandakishore ^[4] ; Chung-Han,Hsieh ^[1] ; Stefano E,Rensi ^[5] ; Russ B,Altman ^[5] ; Michael D,Greicius ^[6] ; Liang,Feng ^[7] ; Xinnan,Wang ^[8]

作者单位： Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA. ^[1] Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Graduate Program of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA. ^[2] Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Institut du Cerveau - Paris Brain Institute - ICM, 75013 Paris, France. ^[3] Vroom Inc., Houston, TX 77042, USA. ^[4] Department of Bioengineering, Stanford University, Stanford, CA 94305, USA. ^[5] Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA. ^[6] Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA. ^[7] Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: xinnanw@stanford.edu. ^[8]

关键词 CP: Neuroscience

主题词人类(Humans);钙(Calcium);帕金森病(Parkinson Disease);药用制剂(Pharmaceutical Preparations);铁(Iron);线粒体(Mitochondria)

DOI 10.1016/j.celrep.2023.113544

PMID 38060381

发布时间 2024-02-10

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