Assessment of antibiotic release and antibacterial efficacy from pendant glutathione hydrogels using ex vivo porcine skin.

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作者： Angeliki,Andrianopoulou ^[1] ; Karol,Sokolowski ^[1] ; Eric,Wenzler ^[2] ; Zackery P,Bulman ^[2] ; Richard A,Gemeinhart ^[3]

作者单位： Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA. ^[1] Department of Pharmacy Practice, University of Illinois Chicago, Chicago, IL, USA. ^[2] Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA; Department of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, USA; Department of Chemical Engineering, University of Illinois Chicago, Chicago, IL, USA; Department of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, USA. Electronic address: rag@uic.edu. ^[3]

关键词 Antibiotic delivery Ex vivo infection model Hydrogel Skin infection Topical drug delivery

主题词动物(Animals);猪(Swine);抗菌药(Anti-Bacterial Agents);万古霉素(Vancomycin);水凝胶类(Hydrogels);金黄色葡萄球菌(Staphylococcus aureus);生物相容性材料(Biocompatible Materials)

DOI 10.1016/j.jconrel.2023.12.008

PMID 38070603

发布时间 2025-01-04

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