Exploiting autophagy balance in T and NK cells as a new strategy to implement adoptive cell therapies.

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第一作者： Manuela,Giansanti

第一单位： Immunology Research Area, Innate Lymphoid Cells Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy.

作者： Manuela,Giansanti ^[1] ; Tobias,Theinert ^[2] ; Sarah Katharina,Boeing ^[2] ; Dorothee,Haas ^[2] ; Paul-Gerhardt,Schlegel ^[2] ; Paola,Vacca ^[1] ; Francesca,Nazio ^[3] ; Ignazio,Caruana ^[4]

作者单位： Immunology Research Area, Innate Lymphoid Cells Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy. ^[1] Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University Hospital Würzburg, 97080, Würzburg, Germany. ^[2] Immunology Research Area, Innate Lymphoid Cells Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy. francesca.nazio@uniroma2.it.;Department of Biology, University of Rome Tor Vergata, 00133, Rome, Italy. francesca.nazio@uniroma2.it. ^[3] Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University Hospital Würzburg, 97080, Würzburg, Germany. caruana_i@ukw.de. ^[4]

关键词 Autophagy Effector cells Metabolism Mitophagy T and NK development

主题词人类(Humans);免疫, 先天(Immunity, Innate);杀伤细胞, 天然(Killer Cells, Natural);T淋巴细胞(T-Lymphocytes);肿瘤(Neoplasms);自噬(Autophagy)

DOI 10.1186/s12943-023-01893-w

PMID 38071322

发布时间 2024-02-28

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