Cytochrome P450 2B6 and UDP-Glucuronosyltransferase Enzyme-Mediated Clearance of Ciprofol (HSK3486) in Humans: The Role of Hepatic and Extrahepatic Metabolism.

导出 LinkOut

翻译打印收藏纠错

第一作者： Yufan,Zhou

第一单位： Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Z., L.L., Y.W., X.C.); University of Chinese Academy of Sciences, Beijing, China (Y.Z., X.C.); Haisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan Province, China (H.D., J.F., M.Z., P.T.); and MassDefect Technologies, Princeton, New Jersey (M.Z.).

作者： Yufan,Zhou ^[1] ; Hongjiao,Dong ^[1] ; Jiang,Fan ^[1] ; Mingshe,Zhu ^[1] ; Lu,Liu ^[1] ; Yongbin,Wang ^[1] ; Pingming,Tang ^[2] ; Xiaoyan,Chen ^[2]

作者单位： Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Z., L.L., Y.W., X.C.); University of Chinese Academy of Sciences, Beijing, China (Y.Z., X.C.); Haisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan Province, China (H.D., J.F., M.Z., P.T.); and MassDefect Technologies, Princeton, New Jersey (M.Z.). ^[1] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Z., L.L., Y.W., X.C.); University of Chinese Academy of Sciences, Beijing, China (Y.Z., X.C.); Haisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan Province, China (H.D., J.F., M.Z., P.T.); and MassDefect Technologies, Princeton, New Jersey (M.Z.) xychen@simm.ac.cn tangpm@haisco.com. ^[2]

主题词人类(Humans);葡糖醛酸甙类(Glucuronides);葡糖醛酸基转移酶(Glucuronosyltransferase);肝(Liver);微粒体, 肝(Microsomes, Liver);尿苷二磷酸(Uridine Diphosphate)

DOI 10.1124/dmd.123.001484

PMID 38071562

发布时间 2025-02-12

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交