Comparison of the inoculum effect of in vitro antibacterial activity of Imipenem/relebactam and Ceftazidime/avibactam against ESBL-, KPC- and AmpC-producing Escherichia coli and Klebsiella pneumoniae.

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作者： Xueting,Wang ^[1] ; Luying,Xiong ^[1] ; Yuan,Wang ^[1] ; Kai,Yang ^[2] ; Tingting,Xiao ^[1] ; Xiaohui,Chi ^[1] ; Tao,Chen ^[1] ; Yanzi,Zhou ^[3] ; Ping,Lu ^[1] ; Dilimulati,Dilinuer ^[1] ; Pin,Shen ^[1] ; Yunbo,Chen ^[1] ; Yonghong,Xiao ^[4]

作者单位： Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. ^[1] Fuwai Yunnan Cardiovascular Hospital, Kunming, China. ^[2] Department of Rheumatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, China. ^[3] Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. xiaoyonghong@zju.edu.cn. ^[4] Jinan Microecological Biomedicine Shandong Laboratory, Jinan, China. xiaoyonghong@zju.edu.cn. ^[5] Research Units of Infectious Disease and Microecology, Chinese Academy of Medical Sciences, Beijing, China. xiaoyonghong@zju.edu.cn. ^[6]

关键词 AmpC Ceftazidime/avibactam ESBL Imipenem/relebactam In vitro PK/PD study Inoculum effect KPC