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Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.

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第一作者: Jack,Humphrey
第一单位: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
作者单位: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. [1] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, USA.;Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA. [2] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA. [3] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Biochemistry and Molecular Biology, Faculty of Medicine (Universidad Complutense de Madrid), Madrid, Spain.;Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.;Instituto Ramon y Cajal de Investigacion Sanitaria (IRYCIS), Madrid, Spain. [4] Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA. [5] Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA. [6] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. [7] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. [8] Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA. [9] Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Mental Illness Research Education, and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, USA. [10] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, USA.;Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA.;Mental Illness Research Education, and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, USA. [11]
DOI 10.1101/2023.12.01.23299073
PMID 38076956
发布时间 2025-03-14
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