A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.

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第一作者： Sopisa,Benjakul

第一单位： Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo 0372, Norway.

作者： Sopisa,Benjakul ^[1] ; Aina Karen,Anthi ^[2] ; Anette,Kolderup ^[3] ; Marina,Vaysburd ^[1] ; Heidrun Elisabeth,Lode ^[2] ; Donna,Mallery ^[3] ; Even,Fossum ^[1] ; Elisabeth Lea,Vikse ^[2] ; Anna,Albecka ^[3] ; Aleksandr,Ianevski ^[4] ; Denis,Kainov ^[1] ; Karine Flem,Karlsen ^[2] ; Siri Aastedatter,Sakya ^[5] ; Mari,Nyquist-Andersen ^[4] ; Torleif Tollefsrud,Gjølberg ^[6] ; Morten C,Moe ^[6] ; Magnar,Bjørås ^[4] ; Inger,Sandlie ^[7] ; Leo C,James ^[7] ; Jan Terje,Andersen ^[8]

作者单位： Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo 0372, Norway. ^[1] Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo 0372, Norway. ^[2] Precision Immunotherapy Alliance (PRIMA), University of Oslo, Oslo 0372, Norway. ^[3] Protein and Nucleic Acid Chemistry Division, Medical Research Council, Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. ^[4] Department of Ophthalmology, Oslo University Hospital and University of Oslo, Oslo 0450, Norway. ^[5] Department of Virology, Norwegian Institute of Public Health, Oslo 0213, Norway. ^[6] Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim 7491, Norway. ^[7] Institute of Technology, University of Tartu, Tartu 50411, Estonia. ^[8] Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00290, Finland. ^[9] Department of Biosciences, University of Oslo, Oslo 0371, Norway. ^[10]

关键词 ACE2 FcRn SARS-CoV-2 half-life mucosal delivery

DOI 10.1093/pnasnexus/pgad403

PMID 38077689

发布时间 2024-02-28

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PNAS nexus

2023年2卷12期

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A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.

PNAS nexus

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PNAS nexus

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A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.

PNAS nexus

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PNAS nexus

相关期刊

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