The genetic contribution to the comorbidity of depression and anxiety: a multi-site electronic health records study of almost 178 000 people.

导出 OA

翻译打印收藏纠错

第一作者： Brandon J,Coombes

第一单位： Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.

作者： Brandon J,Coombes ^[1] ; Isotta,Landi ^[2] ; Karmel W,Choi ^[3] ; Kritika,Singh ^[4] ; Brian,Fennessy ^[5] ; Greg D,Jenkins ^[6] ; Anthony,Batzler ^[7] ; Richard,Pendegraft ^[8] ; Nicolas A,Nunez ^[9] ; Y Nina,Gao ^[10] ; Euijung,Ryu ^[3] ; Priya,Wickramaratne ^[1] ; Myrna M,Weissman ^[1] ; Regeneron Genetics Center ^[1] ; Jyotishman,Pathak ^[11] ; J John,Mann ^[12] ; Jordan W,Smoller ^[1] ; Lea K,Davis ^[12] ; Mark,Olfson ^[12] ; Alexander W,Charney ^[13] ; Joanna M,Biernacka ^[14]

作者单位： Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. ^[1] Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[2] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[3] Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[4] Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[5] Department of Psychiatry, Center for Precision Psychiatry, Massachusetts General Hospital, Boston, MA, USA. ^[6] Psychiatric & Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. ^[7] Department of Psychiatry, Harvard Medical School, Boston, MA, USA. ^[8] Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. ^[9] Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. ^[10] Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA. ^[11] Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, USA. ^[12] Department of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA. ^[13] Clinical and Translational Science Center, Weill Cornell Medicine, New York, New York, USA. ^[14] Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA. ^[15]

关键词 Anxiety depression electronic health records polygenic risk