SHP-1 Regulates CD8+ T Cell Effector Function but Plays a Subtle Role with SHP-2 in T Cell Exhaustion Due to a Stage-Specific Nonredundant Functional Relay.

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第一作者： Bowen,Hou

第一单位： State Key Laboratory of Cellular Stress Biology, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.;School of Life Sciences, Xiamen University, Xiamen, China.

作者： Bowen,Hou ^[1] ; Yanyan,Hu ^[1] ; Yuzhen,Zhu ^[1] ; Xiaocui,Wang ^[1] ; Wanyun,Li ^[2] ; Jian,Tang ^[1] ; Xian,Jia ^[1] ; Jiayu,Wang ^[2] ; Yu,Cong ^[2] ; Minxue,Quan ^[2] ; Hongying,Yang ^[2] ; Haiping,Zheng ^[2] ; Yuzhou,Bao ^[2] ; Xiao Lei,Chen ^[2] ; Hong-Rui,Wang ^[3] ; Bing,Xu ^[4] ; Nicholas R J,Gascoigne ^[5] ; Guo,Fu ^[6]

作者单位： State Key Laboratory of Cellular Stress Biology, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.;School of Life Sciences, Xiamen University, Xiamen, China. ^[1] State Key Laboratory of Cellular Stress Biology, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China. ^[2] School of Life Sciences, Xiamen University, Xiamen, China. ^[3] Department of Hematology, The First Affiliated Hospital and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China. ^[4] Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.;Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. ^[5] State Key Laboratory of Cellular Stress Biology, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.;Department of Hematology, The First Affiliated Hospital and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China.;Cancer Research Center of Xiamen University, Xiamen, China.;Laboratory Animal Center, Xiamen University; Xiamen, China. ^[6]