Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping.
第一作者:
Kenza,Abouir
第一单位:
Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, Geneva, Switzerland; School of Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland. Electronic address: Kenza.abouir@unige.ch.
作者:
医学主题词
人类(Humans);奥美拉唑(Omeprazole);色谱法, 液相(Chromatography, Liquid);芳基烃羟化酶类(Aryl Hydrocarbon Hydroxylases);串联质谱法(Tandem Mass Spectrometry);纤维素(Cellulose);2-吡啶甲基亚硫酰苯咪唑类(2-Pyridinylmethylsulfinylbenzimidazoles)
DOI
10.1016/j.jchromb.2023.123962
PMID
38096743
发布时间
2024-01-15
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