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Suppression of tumour growth from transplanted astrocytoma cells transfected with luciferase in mice by bioluminescence mediated, systemic, photodynamic therapy.

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第一作者： Jane,Ng

第一单位： UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom; National Medical Laser Centre (now Department of Targeted Intervention, Division of Surgery and Interventional Science), University College London, Charles Bell House 43-45 Foley Street, London W1W 7TS, United Kingdom.

作者： Jane,Ng ^[1] ; Nico,Henriquez ^[2] ; Neil,Kitchen ^[3] ; Norman,Williams ^[4] ; Marco,Novelli ^[5] ; Dahmane,Oukrif ^[5] ; Alexander,MacRobert ^[6] ; Stephen,Bown ^[7]

作者单位： UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom; National Medical Laser Centre (now Department of Targeted Intervention, Division of Surgery and Interventional Science), University College London, Charles Bell House 43-45 Foley Street, London W1W 7TS, United Kingdom. ^[1] UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom. ^[2] Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, UCLH NHS Trust, Queen Square, London WC1 3BG, United Kingdom of Great Britain and Northern Ireland, United Kingdom. ^[3] Division of Surgery & Interventional Science, University College London, Charles Bell House, 43-45 Foley Street London W1W 7TS, United Kingdom. ^[4] Department of Cellular Pathology, University College Hospital, London, 60 Whitfield Street, London W1T 4EU, United Kingdom. ^[5] National Medical Laser Centre (now Department of Targeted Intervention, Division of Surgery and Interventional Science), University College London, Charles Bell House 43-45 Foley Street, London W1W 7TS, United Kingdom. ^[6] National Medical Laser Centre (now Department of Targeted Intervention, Division of Surgery and Interventional Science), University College London, Charles Bell House 43-45 Foley Street, London W1W 7TS, United Kingdom. Electronic address: s.bown@ucl.ac.uk. ^[7]

关键词 Bioluminescence mediated photodynamic therapy (bPDT)Grade 4 astrocytoma cells Subcutaneous and intracranial tumour growth suppression Transfection of cells with luciferase mTHPC