Evaluating the Effect of Data Merging and Postacquisition Normalization on Statistical Analysis of Untargeted High-Resolution Mass Spectrometry Based Urinary Metabolomics Data.

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第一作者： Fynn,Brix

第一单位： Institute of Human Nutrition and Food Science, Kiel University, Kiel, Heinrich-Hecht-Platz 10, 24118 Kiel, Germany.

作者： Fynn,Brix ^[1] ; Tobias,Demetrowitsch ^[1] ; Julia,Jensen-Kroll ^[1] ; Helena U,Zacharias ^[2] ; Silke,Szymczak ^[3] ; Matthias,Laudes ^[4] ; Stefan,Schreiber ^[5] ; Karin,Schwarz ^[3]

作者单位： Institute of Human Nutrition and Food Science, Kiel University, Kiel, Heinrich-Hecht-Platz 10, 24118 Kiel, Germany. ^[1] Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, 30625 Hannover, Germany. ^[2] Department of Internal Medicine I, University Medical Centre Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. ^[3] Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. ^[4] Institute of Medical Biometry and Statistics, University of Luebeck and Medical Centre Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany. ^[5] Institute of Diabetes and Clinical Metabolic Research, Kiel University, Düsternbrooker Weg 17, 24105 Kiel, Germany. ^[6]

主题词人类(Humans);质谱分析法(Mass Spectrometry);代谢组学(Metabolomics);肌酸酐(Creatinine)

DOI 10.1021/acs.analchem.3c01380

PMID 38113356

发布时间 2024-02-13

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