SNP (A > G - rs13057211) but not GT(n) polymorphism in HMOX-1 promotor gene is associated with COVID-19 mortality.

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第一作者： Kerolos,Fares

第一单位： Department of Chemical Pathology, Medical Research Institute, Alexandria University, Alexandria, Egypt.

作者： Kerolos,Fares ^[1] ; Mona K,El-Deeb ^[1] ; Omar,Elsammak ^[2] ; Amged,Ouf ^[3] ; Hesham Mahmoud Sayd,Saeed ^[4] ; Ayman,Baess ^[5] ; Mohamed,Elsammak ^[6] ; Eman,El-Attar ^[7]

作者单位： Department of Chemical Pathology, Medical Research Institute, Alexandria University, Alexandria, Egypt. ^[1] Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Al Jouf University, Sakakah, Saudi Arabia. ^[2] Faculty of Medicine, Alexandria University, Alexandria, Egypt. ^[3] Department of Biology and Biotechnology Graduate Program, School of Sciences and Engineering (SSE), The American University in Cairo (AUC), New Cairo, Egypt. ^[4] Department of Biotechnology, Institute of Graduate Studies and Research Alexandria University, Alexandria, Egypt. ^[5] Department of Chest Diseases, Faculty of Medicine, Alexandria University, Alexandria, Egypt. ^[6] Department of Chemical Pathology, Medical Research Institute, Alexandria University, Alexandria, Egypt. Mohamed.elsammak@alexu.edu.eg. ^[7]

关键词 COVID-19 IL-6 Promoter GT(n) polymorphism SNP Serum Hemoxygenase-1

主题词人类(Humans);白细胞介素6(Interleukin-6);多态性, 单核苷酸(Polymorphism, Single Nucleotide);启动区, 遗传(Promoter Regions, Genetic)

DOI 10.1186/s12890-023-02785-x

PMID 38129860

发布时间 2024-01-03

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