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首页> Annals of hematology> Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells.

Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells.

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作者： Wei,Hu ^[1] ; Jingqi,Sun ^[1] ; Yanyan,Zhang ^[1] ; Ting,Chen ^[1] ; Fen,He ^[1] ; Hongyan,Zhao ^[1] ; Weihong,Tan ^[1] ; Zhijian,Wang ^[1] ; Jiaqi,Ouyang ^[1] ; Zhanyou,Tang ^[1] ; Jiarui,He ^[1] ; Jiayu,Wang ^[1] ; Junjun,Li ^[2] ; Xi,Zeng ^[3] ; Jiliang,Xia ^[4]

作者单位： Hunan Province Key Laboratory of Tumor Cellular & Molecular Pathology, Cancer Research Institute, Hengyang Medical School, University of South China, Changshengxi Road 28#, Hengyang, 421001, Hunan, China. ^[1] Department of Hematology, Hengyang Medical School, The First Affiliated Hospital, University of South China, Hengyang, Hunan, China. hylijunjun@163.com. ^[2] Hunan Province Key Laboratory of Tumor Cellular & Molecular Pathology, Cancer Research Institute, Hengyang Medical School, University of South China, Changshengxi Road 28#, Hengyang, 421001, Hunan, China. xzeng@usc.edu.cn. ^[3] Hunan Province Key Laboratory of Tumor Cellular & Molecular Pathology, Cancer Research Institute, Hengyang Medical School, University of South China, Changshengxi Road 28#, Hengyang, 421001, Hunan, China. jiliang-xia@usc.edu.cn. ^[4]

关键词 Apoptosis DNA damage Diallyl disulfide Multiple myeloma Reactive oxygen species

主题词人类(Humans);活性氧(Reactive Oxygen Species);美法仑(Melphalan);多发性骨髓瘤(Multiple Myeloma);DNA损伤(DNA Damage);细胞凋亡(Apoptosis);复方合剂(Drug Combinations);烯丙化合物(Allyl Compounds);二硫化物类(Disulfides);4-乙酰氨基-4'-异氰酸芪-2,2'-二磺酸(4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid)

DOI 10.1007/s00277-023-05592-w

PMID 38148345

发布时间 2024-03-27

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Annals of hematology

Annals of hematology

2024年103卷4期

1293-1303页

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Annals of hematology

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Annals of hematology

2024年103卷4期

1293-1303页

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