Decitabine induces IRF7-mediated immune responses in p53-mutated triple-negative breast cancer: a clinical and translational study.

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作者： Haoyu,Wang ^[1] ; Zhengyuan,Wang ^[2] ; Zheng,Wang ^[1] ; Xiaoyang,Li ^[3] ; Yuntong,Li ^[2] ; Ni,Yan ^[2] ; Lili,Wu ^[2] ; Ying,Liang ^[2] ; Jiale,Wu ^[2] ; Huaxin,Song ^[2] ; Qing,Qu ^[1] ; Jiahui,Huang ^[1] ; Chunkang,Chang ^[4] ; Kunwei,Shen ^[5] ; Xiaosong,Chen ^[6] ; Min,Lu ^[7]

作者单位： Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ^[1] Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine (Shanghai), Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ^[2] Department of Hematology, Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ^[3] Department of Hematology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200025, China. ^[4] Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. kwshen@medmail.com.cn. ^[5] Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. chenxiaosong0156@hotmail.com. ^[6] Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine (Shanghai), Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. min.lu@shsmu.edu.cn. ^[7]

关键词 DNMT1 IRF7 decitabine innate immune response p53 mutation triple-negative breast cancer

主题词人类(Humans);女(雌)性(Female);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);中年人(Middle Aged);突变(Mutation);回顾性研究(Retrospective Studies);干扰素调节因子7(Interferon Regulatory Factor-7);卡铂(Carboplatin);细胞系, 肿瘤(Cell Line, Tumor);成年人(Adult);前瞻性研究(Prospective Studies);老年人(Aged);抗代谢药, 抗肿瘤(Antimetabolites, Antineoplastic);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols)

DOI 10.1007/s11684-023-1016-8

PMID 38157193

发布时间 2024-06-21

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Frontiers of medicine

2024年18卷2期

357-374页

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Decitabine induces IRF7-mediated immune responses in p53-mutated triple-negative breast cancer: a clinical and translational study.

Frontiers of medicine

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Frontiers of medicine

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Decitabine induces IRF7-mediated immune responses in p53-mutated triple-negative breast cancer: a clinical and translational study.

Frontiers of medicine

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Frontiers of medicine

相关期刊

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