Mechanistic insights into the ameliorative effects of Xianglianhuazhuo formula on chronic atrophic gastritis through ferroptosis mediated by YY1/miR-320a/TFRC signal pathway.

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作者： Yuxi,Guo ^[1] ; Xuemei,Jia ^[1] ; Pengli,Du ^[2] ; Jie,Wang ^[1] ; Yao,Du ^[2] ; Bolin,Li ^[2] ; Yucong,Xue ^[3] ; Jianming,Jiang ^[3] ; Yanru,Cai ^[4] ; Qian,Yang ^[5]

作者单位： Department of Spleen and Stomach Diseases, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Heibei, 050011, China. ^[1] Department of Spleen and Stomach Diseases, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Heibei, 050011, China; Hebei Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050011, China; Hebei Key Laboratory of Turbidity Toxin Syndrome, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050011, China. ^[2] College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Heibei, 050200, China. ^[3] Department of Spleen and Stomach Diseases, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Heibei, 050011, China; Hebei Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050011, China; Hebei Key Laboratory of Turbidity Toxin Syndrome, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050011, China. Electronic address: 137544977@qq.com. ^[4] Department of Spleen and Stomach Diseases, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Heibei, 050011, China; Hebei Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050011, China; Hebei Key Laboratory of Turbidity Toxin Syndrome, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050011, China. Electronic address: yang0311qian@126.com. ^[5]

关键词 Chronic atrophic gastritis Ferroptosis TFRC Xianglianhuazhuo formula YY1 miR-320a

主题词大鼠(Rats);动物(Animals);微RNAs(MicroRNAs);胃炎, 萎缩性(Gastritis, Atrophic);信号传导(Signal Transduction);细胞增殖(Cell Proliferation)

DOI 10.1016/j.jep.2023.117608

PMID 38158098

发布时间 2024-01-29

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