Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials.

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作者： Tien Y,Wong ^[1] ; Zdenka,Haskova ^[2] ; Kemal,Asik ^[2] ; Caroline R,Baumal ^[3] ; Karl G,Csaky ^[4] ; Nicole,Eter ^[5] ; Jane A,Ives ^[6] ; Glenn J,Jaffe ^[7] ; Jean-François,Korobelnik ^[8] ; Hugh,Lin ^[2] ; Toshinori,Murata ^[9] ; Paisan,Ruamviboonsuk ^[10] ; Patricio G,Schlottmann ^[11] ; András I,Seres ^[12] ; David,Silverman ^[6] ; Xiaodong,Sun ^[13] ; Yannan,Tang ^[2] ; John A,Wells ^[14] ; Young Hee,Yoon ^[15] ; Charles C,Wykoff ^[16] ; YOSEMITE and RHINE Investigators

作者单位： Tsinghua Medicine, Tsinghua University, Beijing, China, and Singapore National Eye Centre, Singapore, Republic of Singapore. Electronic address: wongtienyin@tsinghua.edu.cn. ^[1] Genentech, Inc., South San Francisco, California. ^[2] New England Eye Center, Tufts Medical Center, Boston, Massachusetts. ^[3] Retina Foundation of the Southwest, Dallas, Texas. ^[4] Department of Ophthalmology, University of Münster, Münster, Germany. ^[5] Roche Products Ltd., Welwyn Garden City, United Kingdom. ^[6] Department of Ophthalmology, Duke University, Durham, North Carolina. ^[7] Centre Hospitalier Universitaire (CHU) de Bordeaux, Service d'Ophtalmologie, Université de Bordeaux, INSERM, BPH, UMR1219, Bordeaux, France. ^[8] Department of Ophthalmology, Shinshu University, Nagano, Japan. ^[9] Department of Ophthalmology, College of Medicine, Rangsit University, Rajavithi Hospital, Bangkok, Thailand. ^[10] Organización Médica de Investigación, Buenos Aires, Argentina. ^[11] Budapest Retina Associates, Budapest, Hungary. ^[12] Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ^[13] Palmetto Retina Center, Retina Consultants of America, Columbia, South Carolina. ^[14] Department of Ophthalmology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, South Korea. ^[15] Retina Consultants of Texas, Retina Consultants of America, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas. ^[16]

关键词 Angiopoietin-2 Diabetic macular edema Faricimab Vascular endothelial growth factor A Vascular stability